Since Patrons often trip people up, here is a brief overview of everything you need regarding patrons. This is also available in the FAQ on Discord, but I am getting it nicely done up by the overlords as well.

When you create your crew, they may know a number of Patrons. These are people you have done work for in the past.

In the first turn of the campaign, each known Patron will give you a job offer. This is a one time benefit to get you started. 

Normally to get a Patron job you have to take the "Find a Patron" action. Your number of known Patrons is added to the die roll for this action, so if you began the campaign with 2, you would add 2 to the roll. On a final roll of a 5 you get a job offer. This is from one of your existing known Patrons (if you have any). If the roll is a 6 or more you get an offer from an existing Patron and an offer from a new Patron. 

Patrons become known and add to future Find a Patron rolls if you accept their job and successfully complete it. 

The Patrons you begin the game with are also known automatically (You completed a job for them before the campaign started).

Once a Patron is known you can decline jobs from them without any risk. They remain known.

If you fail a job for a known Patron, they are removed from your known list ("We are concerned about your recent performance" / "we have decided to synergise with a different freelancer brand" / you blew up an orphanage for robot children).

You are allowed to accept multiple jobs at the same time, if the time limits permit. A job that isnt completed by the time limit is considered to have failed.